Efficacy of pentavalent rotavirus vaccine in a high HIV prevalence population in Kenya.
Identifieur interne : 000731 ( Main/Exploration ); précédent : 000730; suivant : 000732Efficacy of pentavalent rotavirus vaccine in a high HIV prevalence population in Kenya.
Auteurs : Daniel R. Feikin [Kenya] ; Kayla F. Laserson ; Joel Ojwando ; Geoffrey Nyambane ; Victor Ssempijja ; Allan Audi ; Daveline Nyakundi ; Janet Oyieko ; Michael J. Dallas ; Max Ciarlet ; Kathleen M. Neuzil ; Robert F. BreimanSource :
- Vaccine [ 1873-2518 ] ; 2012.
Descripteurs français
- KwdFr :
- Administration par voie orale, Femelle, Fèces (virologie), Gastroentérite (), Gastroentérite (anatomopathologie), Gastroentérite (épidémiologie), Génotype, Humains, Incidence, Infections à VIH (), Infections à VIH (immunologie), Infections à rotavirus (), Infections à rotavirus (anatomopathologie), Infections à rotavirus (épidémiologie), Kenya (épidémiologie), Mâle, Méthode en double aveugle, Nourrisson, Placebo (administration et posologie), Rotavirus (), Rotavirus (génétique), Rotavirus (isolement et purification), Vaccination (), Vaccins anti-rotavirus (administration et posologie), Vaccins anti-rotavirus (immunologie), Vaccins atténués (administration et posologie), Vaccins atténués (immunologie).
- MESH :
- administration et posologie : Placebo, Vaccins anti-rotavirus, Vaccins atténués.
- anatomopathologie : Gastroentérite, Infections à rotavirus.
- génétique : Rotavirus.
- immunologie : Infections à VIH, Vaccins anti-rotavirus, Vaccins atténués.
- isolement et purification : Rotavirus.
- virologie : Fèces.
- épidémiologie : Gastroentérite, Infections à rotavirus, Kenya.
- Administration par voie orale, Femelle, Gastroentérite, Génotype, Humains, Incidence, Infections à VIH, Infections à rotavirus, Mâle, Méthode en double aveugle, Nourrisson, Rotavirus, Vaccination.
- Wicri :
- geographic : Kenya.
English descriptors
- KwdEn :
- Administration, Oral, Double-Blind Method, Feces (virology), Female, Gastroenteritis (epidemiology), Gastroenteritis (pathology), Gastroenteritis (prevention & control), Genotype, HIV Infections (complications), HIV Infections (immunology), Humans, Incidence, Infant, Kenya (epidemiology), Male, Placebos (administration & dosage), Rotavirus (classification), Rotavirus (genetics), Rotavirus (isolation & purification), Rotavirus Infections (epidemiology), Rotavirus Infections (pathology), Rotavirus Infections (prevention & control), Rotavirus Vaccines (administration & dosage), Rotavirus Vaccines (immunology), Vaccination (methods), Vaccines, Attenuated (administration & dosage), Vaccines, Attenuated (immunology).
- MESH :
- chemical , administration & dosage : Placebos, Rotavirus Vaccines, Vaccines, Attenuated.
- geographic , epidemiology : Kenya.
- classification : Rotavirus.
- complications : HIV Infections.
- epidemiology : Gastroenteritis, Rotavirus Infections.
- genetics : Rotavirus.
- immunology : HIV Infections, Rotavirus Vaccines, Vaccines, Attenuated.
- isolation & purification : Rotavirus.
- methods : Vaccination.
- pathology : Gastroenteritis, Rotavirus Infections.
- prevention & control : Gastroenteritis, Rotavirus Infections.
- virology : Feces.
- Administration, Oral, Double-Blind Method, Female, Genotype, Humans, Incidence, Infant, Male.
Abstract
Rotavirus gastroenteritis (RVGE) is a leading cause of death in African children. The efficacy of pentavalent rotavirus vaccine (PRV) against severe RVGE evaluated in Ghana, Kenya, and Mali in a randomized, double-blind, placebo-controlled trial, showed a combined regional efficacy of 39.3% (95% confidence interval [CI]: 19.1,54.7) in nearly 2 years of follow-up. This report concentrates on the Kenya findings.
DOI: 10.1016/j.vaccine.2011.08.043
PubMed: 22520137
Affiliations:
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Le document en format XML
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(pathology)</term><term>Rotavirus Infections (prevention & control)</term><term>Rotavirus Vaccines (administration & dosage)</term><term>Rotavirus Vaccines (immunology)</term><term>Vaccination (methods)</term><term>Vaccines, Attenuated (administration & dosage)</term><term>Vaccines, Attenuated (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Administration par voie orale</term><term>Femelle</term><term>Fèces (virologie)</term><term>Gastroentérite ()</term><term>Gastroentérite (anatomopathologie)</term><term>Gastroentérite (épidémiologie)</term><term>Génotype</term><term>Humains</term><term>Incidence</term><term>Infections à VIH ()</term><term>Infections à VIH (immunologie)</term><term>Infections à rotavirus ()</term><term>Infections à rotavirus (anatomopathologie)</term><term>Infections à rotavirus (épidémiologie)</term><term>Kenya (épidémiologie)</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nourrisson</term><term>Placebo (administration et posologie)</term><term>Rotavirus ()</term><term>Rotavirus (génétique)</term><term>Rotavirus (isolement et purification)</term><term>Vaccination ()</term><term>Vaccins anti-rotavirus (administration et posologie)</term><term>Vaccins anti-rotavirus (immunologie)</term><term>Vaccins atténués (administration et posologie)</term><term>Vaccins atténués (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Placebos</term><term>Rotavirus Vaccines</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Kenya</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Placebo</term><term>Vaccins anti-rotavirus</term><term>Vaccins atténués</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Gastroentérite</term><term>Infections à rotavirus</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Rotavirus</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Gastroenteritis</term><term>Rotavirus Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Rotavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Rotavirus</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à VIH</term><term>Vaccins anti-rotavirus</term><term>Vaccins atténués</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV Infections</term><term>Rotavirus Vaccines</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Rotavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Rotavirus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Gastroenteritis</term><term>Rotavirus Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Gastroenteritis</term><term>Rotavirus Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fèces</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Feces</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Gastroentérite</term><term>Infections à rotavirus</term><term>Kenya</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Double-Blind Method</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Incidence</term><term>Infant</term><term>Male</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie orale</term><term>Femelle</term><term>Gastroentérite</term><term>Génotype</term><term>Humains</term><term>Incidence</term><term>Infections à VIH</term><term>Infections à rotavirus</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nourrisson</term><term>Rotavirus</term><term>Vaccination</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Kenya</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Rotavirus gastroenteritis (RVGE) is a leading cause of death in African children. The efficacy of pentavalent rotavirus vaccine (PRV) against severe RVGE evaluated in Ghana, Kenya, and Mali in a randomized, double-blind, placebo-controlled trial, showed a combined regional efficacy of 39.3% (95% confidence interval [CI]: 19.1,54.7) in nearly 2 years of follow-up. This report concentrates on the Kenya findings.</div></front></TEI><affiliations><list><country><li>Kenya</li></country></list><tree><noCountry><name sortKey="Audi, Allan" sort="Audi, Allan" uniqKey="Audi A" first="Allan" last="Audi">Allan Audi</name><name sortKey="Breiman, Robert F" sort="Breiman, Robert F" uniqKey="Breiman R" first="Robert F" last="Breiman">Robert F. Breiman</name><name sortKey="Ciarlet, Max" sort="Ciarlet, Max" uniqKey="Ciarlet M" first="Max" last="Ciarlet">Max Ciarlet</name><name sortKey="Dallas, Michael J" sort="Dallas, Michael J" uniqKey="Dallas M" first="Michael J" last="Dallas">Michael J. Dallas</name><name sortKey="Laserson, Kayla F" sort="Laserson, Kayla F" uniqKey="Laserson K" first="Kayla F" last="Laserson">Kayla F. Laserson</name><name sortKey="Neuzil, Kathleen M" sort="Neuzil, Kathleen M" uniqKey="Neuzil K" first="Kathleen M" last="Neuzil">Kathleen M. Neuzil</name><name sortKey="Nyakundi, Daveline" sort="Nyakundi, Daveline" uniqKey="Nyakundi D" first="Daveline" last="Nyakundi">Daveline Nyakundi</name><name sortKey="Nyambane, Geoffrey" sort="Nyambane, Geoffrey" uniqKey="Nyambane G" first="Geoffrey" last="Nyambane">Geoffrey Nyambane</name><name sortKey="Ojwando, Joel" sort="Ojwando, Joel" uniqKey="Ojwando J" first="Joel" last="Ojwando">Joel Ojwando</name><name sortKey="Oyieko, Janet" sort="Oyieko, Janet" uniqKey="Oyieko J" first="Janet" last="Oyieko">Janet Oyieko</name><name sortKey="Ssempijja, Victor" sort="Ssempijja, Victor" uniqKey="Ssempijja V" first="Victor" last="Ssempijja">Victor Ssempijja</name></noCountry><country name="Kenya"><noRegion><name sortKey="Feikin, Daniel R" sort="Feikin, Daniel R" uniqKey="Feikin D" first="Daniel R" last="Feikin">Daniel R. Feikin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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